Bone Formation During Distraction Osteogenesis Is Dependent on Both VEGFR1 and VEGFR2 Signaling
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چکیده
منابع مشابه
Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling.
INTRODUCTION Distraction osteogenesis (DO) is characterized by the induction of highly vascularized new bone formation through an intramembranous process largely devoid of the formation of cartilage. MATERIALS AND METHODS To test the hypothesis that DO is strictly dependent on vascualrization, we inhibited vascular endothelial growth factor (VEGF) activity by antibody blockade of both recepto...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 2008
ISSN: 0884-0431
DOI: 10.1359/jbmr.080103